Esomeprazole is used to treat:
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Esoral Mups 20mg Tablet contains Esomeprazole, a Proton pump inhibitor used to treat GERD, heartburn, stomach ulcers caused by Helicobacter pylori bacteria or NSAIDs, and Zollinger-Ellison syndrome in adults and adolescents above 12 years of age. It helps by reducing stomach acid to relieve symptoms and promote healing.
However, Esoral Mups 20mg Tablet is not recommended for patients with severe kidney and liver failure. Pregnant women should take it only if necessary and after consulting their doctor. Breastfeeding women should avoid it. Children and adolescents below 12 years should also avoid this medication.
Common side effects of Esoral Mups 20mg Tablet include headache, diarrhea, stomach pain, constipation, flatulence, nausea, and vomiting. If any of these symptoms worsen over time, contact your physician for guidance.
Although there is no known interaction with alcohol, consuming alcohol increases acidity further and worsens issues related to the digestive system. Hence, alcohol should be avoided while on treatment with Esoral Mups 20mg Tablet.
Esoral Mups 20mg Tablet can be used during pregnancy. However, it should be used only under the recommendation of a doctor after assessing if this medicine is beneficial and will not harm the unborn child.
Esoral Mups 20mg Tablet should not be used by lactating mothers as it is not known if this medicine is passed into the breast milk and can have undesirable effects on the nursing infant.
Esoral Mups 20mg Tablet shows side effects like dizziness and blurred vision which can affect your driving ability. If you experience any such symptoms, do not drive.
Esoral Mups 20mg Tablet should be used with caution in patients with severe kidney problems. Consult your doctor before taking Esoral Mups 20mg Tablet.
Esoral Mups 20mg Tablet should be used with caution in patients with severe liver problems. Consult your doctor before taking Esoral Mups 20mg Tablet.
Esoral Mups 20mg Tablet decreases the acid production in your stomach. It also fastens the healing process for ulcers.
Sompraz 40 tablet is used for the treatment of acid reflux disease, stomach and intestinal ulcers, and Zollinger-Ellison syndrome. It contains esomeprazole as its active ingredient.
Esomeprazole is a proton pump inhibitor (PPI) that works by specifically inhibiting the H+/K+ ATPase enzyme in the gastric parietal cells of the stomach. This enzyme is responsible for the final step in the production of gastric acid. By inhibiting this enzyme, esomeprazole reduces the production of stomach acid, which can help in the treatment of conditions such as gastroesophageal reflux disease (GERD), peptic ulcers, and other acid-related disorders.
Esomeprazole is the S-isomer of omeprazole, which means it is a single optical isomer of omeprazole. This single isomer formulation provides better acid control than racemic PPIs (those containing both S and R isomers), making it more effective in acid suppression and providing longer-lasting effects.
Adult Dose:
GERD Without Erosive Esophagitis: 20 mg orally once a day for 4 weeks; consider an additional 4 weeks of treatment if symptoms do not completely resolve in the first 4 weeks.
GERD With Erosive Esophagitis: 20-40 mg orally once a day for 4-8 weeks. If oral therapy is not possible, 20-40 mg intravenously (IV) once a day for up to 10 days, then switch to oral administration once the patient can swallow.
Maintenance: 20 mg orally once a day for up to 6 months.
Risk Reduction of NSAID-Associated Gastric Ulcer: 20-40 mg orally once a day for up to 6 months.
NSAID-Induced Gastric Ulcer: 20 mg orally once a day for 4-8 weeks.
Zollinger-Ellison Syndrome: Initially 80 mg orally divided every 12 hours, adjust regimen to efficacy, up to 240 mg orally once a day or 120 mg orally every 12 hours.
Elderly: No dosage adjustment is needed.
Hepatic Impairment:
Child Dose:
GERD Without Erosive Esophagitis:
12 years: 20-40 mg orally once a day for up to 8 weeks.
GERD With Erosive Esophagitis (Healing):
3.5-7.5 kg: 5 mg orally once a day for up to 6 weeks.
7.5 kg: 10 mg orally once a day for up to 6 weeks.
20 kg: 10-20 mg orally once a day for 8 weeks.
12 years: 20-40 mg orally once a day for 4-8 weeks.
Maintenance: 20 mg orally once a day for up to 6 months.
Renal Dose:
Renal impairment: No dosage adjustment is needed.
Sompraz 40 tablets can interact with other medications, affecting their effectiveness or how Sompraz 40 tablet works. It is crucial to inform your doctor about all the medicines you are taking, including prescribed, non-prescribed, herbal medicines, dietary supplements, and other treatments for any disorders.
Particular caution should be taken if you are using medicines for heart-related disorders like digoxin, brain-related diseases, anti-epileptic medicines like phenytoin, anti-fungal medicines, antipsychotic medicines, etc. Sompraz 40 tablets may decrease the effectiveness of Anti-HIV medicines if taken together.
Additionally, the blood-thinning action of Warfarin may increase when used with Sompraz, leading to a risk of bleeding. Medications like cisapride (used for constipation), clopidogrel (blood-thinner), and tacrolimus (immunosuppressants) should also be used cautiously with Sompraz 40 tablets. Always consult your doctor for guidance to avoid potential interactions and ensure safe and effective treatment.
Esomeprazole is FDA-approved for use during pregnancy and falls under pregnancy category B, indicating that animal studies have not shown any risk to the fetus, but there are no adequate and well-controlled studies in pregnant women.
However, there is no available data on the excretion of Esomeprazole into human milk for nursing mothers. Therefore, caution should be exercised, and nursing mothers should consult their doctors before using Esomeprazole to assess the potential risks and benefits. The decision to use the medication should consider the importance of breastfeeding and the potential impact on the breastfed infant.
Esoral Mups 20mg Tablet should be stored in a cool and dry place. Keep it out of reach of children and pets.
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